Home Chemistry Heterocyclic Building Blocks Other Aliphatic Heterocycles 3-Azabicyclo[3.1.0]Hexane
Nucleophilic Substitution: The nitrogen atom in the compound is nucleophilic and can undergo substitution reactions. For example, it can react with alkyl halides to form N-alkylated products, similar to typical amine reactions.
Acylation: The nitrogen atom can also react with acylating agents, such as acyl chlorides or anhydrides, to form amide derivatives.
Reductive Amination: The compound can participate in reductive amination reactions, where it reacts with a carbonyl compound (e.g., an aldehyde or ketone) and a reducing agent (e.g., sodium cyanoborohydride) to form an amine product.
Ring Opening: The ring can potentially undergo ring-opening reactions under specific conditions, leading to the formation of open-chain compounds.
Hofmann Degradation: Under certain conditions, 3-azabicyclo[3.1.0]hexane can undergo Hofmann degradation, a reaction used to convert primary amides into primary amines.
Oxidation: Depending on the reaction conditions and reagents used, oxidation of the compound may be possible, leading to the formation of various oxidation products.
Catalytic Hydrogenation: The compound can be subjected to catalytic hydrogenation, where the double bond in the ring can be reduced to a single bond in the presence of a suitable catalyst and hydrogen gas.
Cycloadditions: Depending on the reactants and conditions, 3-azabicyclo[3.1.0]hexane can participate in cycloaddition reactions, such as Diels-Alder reactions, which involve the formation of cyclic products.
Redox Reactions: The compound may participate in various redox reactions, especially if it contains functional groups that are amenable to oxidation or reduction.
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(1R,5S,6R)-(3-Azabicyclo[3.1.0]hex-6-yl)methanol
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3-tert-Butoxycarbonyl-3-azabicyclo[3.1.0]hexane-6-carboxylic acid
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3-Azabicyclo[3.1.0]hexan-6-ol hydrochloride
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tert-Butyl (3-azabicyclo[3.1.0]hexan-1-ylmethyl)carbamate
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tert-Butyl ((3-azabicyclo[3.1.0]hexan-6-yl)methyl)(methyl)carbamate
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tert-Butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate
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tert-Butyl 1-(hydroxymethyl)-3-azabicyclo[3.1.0]hexane-3-carboxylate
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6-(BOC-amino)-3-azabicyclo[3.1.0]hexane
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6,6-Difluoro-3-Azabicyclo[3.1.0]hexane HCl
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Ethyl 3-azabicyclo[3.1.0]hexane-6-carboxylate hydrochloride
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3-tert-Butyl 1-ethyl 3-azabicyclo[3.1.0]hexane-1,3-dicarboxylate
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3-(tert-Butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-1-carboxylic acid
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